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how to estimate founder and effective population size from snps data in VCF format

Hi everyone,

I have a filtered SNPS sequence data in VCF format. I need to use this data to estimate the founder size and effective population size (Ne). I have no idea of how to go about it. I got to know the Ne could be estimated through linkage disequilibrium and heterozygote excess. Could anyone recommend a software to estimate those parameters? Thanks

snp

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