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capture-based plasma cnv calling

Hi, Is there any tools can be used to call CNV in capture-based plasma sequencing data? Thanks a lot.

capture-based panel data plasma cnv cnv

1 answer

You could try DNAcopy (R) or Control-FREEC, or just use a customised method that utilises circular binary segmentation (CBS) and adjusts for sequencing depth across samples / libraries and also GC content.

Kevin

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