Combining datasets from different sequencing platforms
Hello,
I'm trying to analyze a whole exome sequencing data with cases-only. I have an external dataset that will be potentially used as a control group. The problem is the external data is imputed array data. I'm wondering if I can combine the two datasets and how to show their compatibility. Thank you for any helps in advance.
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heejin.kim •
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It is going to be very challenging to figure out what differences between your control and your cases is biological, and what differences are caused by batch effect and using a totally different technology.