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How to get genes with best Phylogenetic signal from multiple orthologous genes?

Hello Experts,

I have used BUSCO to get orthologous genes from 50 species. After that, I have sorted the 350 common orthologous genes from 50 species. Now I want to do phylogenetic analysis with the orthologous genes. But using concatenated 350 genes for phylogeny in MrBayes or RaxML is a very time-consuming process. So I want to know is there any simulation software available to get best genes out of 350 which will give better phylogenetic signal for doing the same.

Thank you

phylogeny orthologous simulation

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