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Draw a heat map of linkage disequilibrium R^2s from 10,000 SNPs

I am trying to analyze the correlation structures among SNPs in genes, so I would like to generate heatmaps of the linkage disequilibrium measure R^2. It is useful when the genes include hundreds of SNPs. But I am not sure how to do that with a gene include 10,000+ SNPs? Is there a way to draw heatmaps with 10,000 SNPs?

Thank you in advance!!

snp r

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