What's your favorite and/or "gold standard" RNA-seq datasets for neurodegenerative diseases?
I come from the field of computational cancer genomics where there are some datasets that are well-known as "high-quality" ones in cancer. I want to benchmark some of the computational tools I'm currently developing on RNA-seq datasets for neurodegenerative diseases: I want to make sure I can identify known regulators with the tools I am testing. Therefore, I am looking for high-quality RNA-seq datasets for neurodegenerative diseases. Any advice on where to find such datasets?
1 answer
This dataset by Lister et al. is an excellent dataset for developing human brain (SRR921934-45). It's not neurodegeneration, but you might still be able to test your tools. It's rare to find good quality human brain RNA-seq data.
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