Dear all, I have identified one gene, whose expression influences survival in patients. I tried to replicate the result in another dataset. However, I could …

hello this is the first time that I have to perform a gene abundance profile along several number of samples using genes with different sizes: …

Hello everyone, I was wondering if it is statistically acceptable to perform SKAT-O analysis one a single gene. To elaborate, I am looking in a …

Hello, I need to assess how many individuals I need to sequence to find all variants with an allele frequency <0.001 with a power of …

Hello everybody, I am working on region-based variants association testing from sequencing data with related samples. I know that there are several approaches (Burden testing, …

Hello I usually calculate sample sizes for GWAS using QUANTO. This time, the number of controls is already decided to 800, so QUANTO is not …

Hi all, I'm trying to do an differential expression analysis on RNA-seq data. I have data from controls, patients with a mutation in gene A, …

Hello Everyone, I have two gene lists with sample, gene, chromosome, mutation_type, start, end, codon columns. Want to perform Fishers test between two gene lists …

<p>Hello,</p> <p>I study autoimmune disease. Recently, several groups have reported that T-cell enhancer regions are particularly enriched for candidate causal variants of Rheumatoid Arthritis and …

<p>I need to justify my assumptions and need to calculate the effect size of SNPs (25 in total) vs Body fat percent which range between …