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How to analyze the 450K methylation data from UCSC Xena?

Hi, there,

I am working on the 450k methylation microarray data coming from the UCSC Xena. I plan to use minfi or ChMAP to detect the DMCs and DMRs, but the input files for those two packages are in .idat format. The data come from UCSC Xena is not that kind of format. Any advice and suggestions? Also, I have tried to download the .idat data from TCGA, but TCGA just provides .txt files. Thnanks in advance.

r

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