Drug targets for hub genes
I have done differential expression analysis after which I have constructed the PPI network using the list of DEGs and then used Cytoscape to find the list of hub genes. Now how can I validate that these hub genes and the network that they form is indeed implicated in the disease I am studying. I also read that PPI network formed by hub genes can be used a prime drug targets. Is there any database that will take in the hub gene network and give us a list of drugs that might be used to target them?
0 answers
No answers yet.
Log in to answer this question.
More posts like this
-
Workflow for functional analysis of differential gene core modules: KEGG, GSEA, and GO enrichment
written by mizzika •
-
Is it valuable to identify hubgenes of miRNAs target genes
written by Ant •
-
Filtering out useful targets for mirna
written by Bhanu •
-
Help on software to use to analyze relationship between drug protein targets and disease genes.
written by umarhyper10 •
-
Protein-Protein interaction (Cytoscape)
written by sindhujarajavelu •
-
Hub gene in ppi network not included in list of deg.
written by ghataksoumyakanti •
-
Which should items consider to creste a dru-drug-gene interaction network?
written by carlos_marchi
-
how can I deal with proteins that belong to one gene if I want to I score my PPI ( Protein Protein …
written by AAhmed •
-
How to link disease-associated genes and deferentially expressed genes in a protein-protein intera…
written by Ting-You Wang
-
Visualize regulatory network using cytoscape
written by kim •
Have you tried Open Targets? With your hub genes individually.
thanks for the suggestion. I will look into that. Can you also please suggest some other methods to validate?