Mutated gene based pathway enrichment
My goal is to find dysfunctioned pathways using mutated genes of hundred tumor samples as input.
There are tools like GSEA that take expression data and perform pathway enrichment. I am wondering if there is similar enrichment tools that take mutated genes as input instead and perform enrichment analysis?
1 answer
You can try geneontology or enrichr if you are not an R user. You can also start with this thread Tutorial: Easy way to do GO enrichment in R and take it from there to explore other R packages.
hth
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