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Question: CHIP-SEQ - multiply aligned reads handling
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Do I need to filter out reads that have been aligned more than once before peakcalling with MACS2?

ADD COMMENTlink 11 months ago kozaleo • 0 • updated 9 months ago Biostar 20
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https://groups.google.com/forum/#!topic/macs-announcement/ASQ3GsXQC1c

Depends on the data you are trying to process. If your regions of interest are not repeated you can filter out them before peakcalling

ADD REPLYlink 11 months ago
Bastien Hervé
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