How to compile a list of non-cancerous mutations
0
0
Entering edit mode
5.1 years ago
Gene_MMP8 ▴ 240

I am trying to perform a one-class classification of driver vs non-driver mutations. I have a list of experimentally validated driver mutations from a pancancer study. But is it possible to retrieve a list of non-cancerous mutations as well? Since the number of non-cancerous mutations far exceeds the number drivers, I would train a one-class SVM on the list of non-cancer mutations and predict the outliers as drivers. But before that, I need a list of such high confidence non-cancer mutations. Is there a way to compile a list from different databases?

next-gen sequencing cancer • 732 views
ADD COMMENT

Login before adding your answer.

Traffic: 3923 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6