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Help for glmnet analyzing gene-pairs survival datas.

Hi,

Does anybody know glmnet? I've read some articles, which referred to a gene-pairs conception, and they analyzed survival data within the form of gene-pairs. enter link description here and enter link description here.

What puzzles me is how to prepare the needed data. I know they all need to merge some data as the meta-dataset, but they are still single gene as row names. While the articles above both analyzed gene-pairs (combination with two different genes) survival data with R package glmnet. What is the key point of this transformation?

Any thoughts will be helpful, Thanks for your precious time, and wish you a great day!

glmnet gene-pairs survival analysis

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