Hi,
I need phyloP scpres for the whole human genome. I was able to download 10M positions from http://genome.ucsc.edu/cgi-bin/hgTables using these instructions:
group: Comparative Genomics
track: Conservation
table: your phyloP table of choice
region: genome
output format: data points
However I need the whole genome information, not just 10M.
The website directs me to the downloads page, but I was lost there unfortunately.
Can anyone please link me to the correct place? (Human Grch37 phyloP values in data point format)
Thanks!!
2 answers
A bigwig file for phyloP on hg19 whole genome is here http://hgdownload.cse.ucsc.edu/goldenpath/hg19/phyloP100way/
It's a large 8.9Gb bigwig so I do not necessarily suggest converting this into text format all at once, but you could convert to text using bigWigToBedGraph (or convert small chunks at a time with this tool, which accepts -chrom, -start, and -end arguments)
http://hgdownload.soe.ucsc.edu/admin/exe/linux.x86_64/bigWigToBedGraph
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