Hello,

I am working on a RNAseq dataset and have to make a topGO enrichment (in R). I have downloaded the up-to-date mapping "genes2Go" file from a database. However, when exploring the mapping file, it looks weird since it contains many perfectly duplicated lines.

1. Is this file ok?
2. Will it influence the subsequent topGOenrichment of my data?
3. Does the duplication mean something?

Thanks

Example:

Transcript ID   GO terms
XXXXX42200.1    GO0004252|GO:0006508
XXXXX42200.1    GO0004252|GO:0006508
XXXXX42200.1    GO0004252|GO:0006508
XXXXX42200.1    GO0004252|GO:0006508
XXXXX42200.1    GO0004252|GO:0006508
XXXXX02300.3    GO0005515|GO:0007165
XXXXX02300.3    GO0005515|GO:0007165
XXXXX02300.3    GO0005515|GO:0007165
XXXXX02300.3    GO0005515|GO:0007165
XXXXX02300.3    GO0043531
XXXXX02300.3    GO0005515|GO:0007165
XXXXX05700.2    GO0009058|GO:0016746
XXXXX05700.2    GO0003824|GO:0008152
XXXXX05700.2    GO0003824|GO:0008152
XXXXX05700.2    GO0009058|GO:0016746
XXXXX02300.1    GO0043531
XXXXX02300.1    GO0005515|GO:0007165
XXXXX02300.1    GO0005515|GO:0007165
XXXXX02300.1    GO0005515|GO:0007165
XXXXX02300.1    GO0005515|GO:0007165
XXXXX02300.1    GO0005515|GO:0007165
XXXXX13500.1    GO0003723|GO:0016787|GO:0030145
XXXXX13500.1    GO0016787
XXXXX13500.1    GO0016787
XXXXX13500.1    GO0016787
XXXXX13500.1    GO0016787
XXXXX13500.1    GO0016787
XXXXX13500.2    GO0016787