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Breast oncoprotein oncogene

Where can I find the complete list/database of breast cancer genes and proteins?

proteome protein oncogene oncoprotein

There is no need to SHOUT. I have adapted your title to remove the capital characters.

Thank you so much for your replies - Nicolas Rosewick and Michael Dondrup

2 answers

I am not sure if there can be a complete list or database of Breast cancer genes anywhere, but this article from 2012 contains genes containing driver mutations: https://www.nature.com/articles/nature11017

Then there is of course the COSMIC database. https://cancer.sanger.ac.uk/cosmic Now if you search there for 'breast cancer' with a query like this: https://cancer.sanger.ac.uk/cosmic/browse/tissue?hn=carcinoma&in=t&sh=NS&sn=breast&ss=NS

A better gene set might be retrieved by going to the COSMIC gene census: https://cancer.sanger.ac.uk/cosmic/census?tier=all

and filtering the gene list for 'breast' (723 hits)

You receive over 24000 genes with mutations in one or the other sample. Most of them I propose are passenger mutations, see also: Driver And Passenger Mutations In Cancer

I believe that for a small number of known genes that is constantly expanded and changed, you will be better served by doing a comprehensive literature search through PubMed etc first. The task is to stay aligned with the current state of research and of course find more recent publications than the one I gave first:

Thank you so much for your replies - Michael Dondrup

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Thank you so much for your replies - Nicolas Rosewick

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