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Can anyone help me with Kimura 2 parameter model

Can anyone help me with Kimura 2 parameter model

Please explain me how we have got eq 3.17 from eq 3.16 [1] I am new to evolutionary biology with no math background thus facing problem. I have been able to solve till 3.16 but stuck after that.

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Looking for positive reply

Thanks in advanvce

substitution model
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written by aloke205 • aloke205

This is not bioinformatics, but calculus. The last step has to do with Leibniz's notation, check wiki if that sounds unfamiliar.

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written by Benn Benn

Thanks a lot.. i will have a look at it :)

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written by aloke205 • aloke205

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