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Can someone suggest the tool to Calculate Tumor Mutation Burden from VCF file

How to calculate TMB (Tumor Mutation Burden) from VCF file?. suggest some reliable tools

vcf tumor-mutational-burden r tmb

I can find no direct tools to calculate TMB only from VCF files.

1 answer

Have you tried maftools ?

http://bioconductor.org/packages/release/bioc/html/maftools.html

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