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Amino Acid matrices freely downloadable url

Any resource to d freely download Amino Acid matrices : VTML, OPTIMA, MD, RBLOSUM.

Reference articles do not have such urls or it`s not working!!

Thanks !!

sequence alignment

2 answers

Here's a place to download PAM and BLOSUM matrices (and Dayhoff, GONNETT): ftp://ftp.ncbi.nlm.nih.gov/blast/matrices/

Jones matrices are here: ftp://ftp.ncbi.nih.gov/repository/blocks/unix/blosum/JTT/

RBLOSUM62 and RBLOSUM64 are given here as a PDF: http://web.mit.edu/bamel/blosum/styczynski2007supp.pdf

The VTML200 matrix is given here: http://www.drive5.com/pop/VTML200I

PFASUM matrices are available here (via PDF and tar.gz) from the project website: http://www.cbs.tu-darmstadt.de/PFASUM/

OPTIMA matrix is given as a PDF in Kann M, Qian B, Goldstein RA. Optimization of a new score function for the detection of remote homologs. Proteins. 2000 Dec 1;41(4):498-503. PubMed PMID: 11056037.

Thanks ... !! Similar to BLOSUM and PAM, does we have any resource for VTML series of matrices ??

See the link POP. You can also find some references and original scripts to generate the matrix there.

Hi, I'm quiet new to evolution, do you know why there is so many version of Jones matrices there? Thank you very much.

BLOSUM and PAM series matrices are available on NCBI ftp. See this link: ftp://ftp.ncbi.nih.gov/blast/matrices/

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