Hi everyone!
Are there any special or classic techniques for finding potential drug targets with RNA-seq analysis? Say, we have 2 conditions (normal and disease) and it's time-series data (4-5 time points). Should we build gene-regulatory networks and look at DE genes/proteins that form connection "hot spots" (interact with big number of proteins/genes)? Or there are other and better ways? Sorry, just entered this field, maybe there are indeed classical approaches for this type of analysis. Thanks!
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written
by
chipolino •
1 answer
There are "many" options, as expressed by my colleague, Malachi: Drug to Target/Gene/Protein Interaction Databases
His post was > 6 years ago (currently August, 2018), so, a lot of those may have been updated or may not even exist any longer.
Other ones of which I know include:
[Note: open PHACTS links together many other databases.]
My own experience of working with these databases is that they hold much promise.
Kevin
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