Biostar Beta. Not for public use.
RNA-seq for drug targets
Entering edit mode
19 months ago
chipolino • 40

Hi everyone!

Are there any special or classic techniques for finding potential drug targets with RNA-seq analysis? Say, we have 2 conditions (normal and disease) and it's time-series data (4-5 time points). Should we build gene-regulatory networks and look at DE genes/proteins that form connection "hot spots" (interact with big number of proteins/genes)? Or there are other and better ways? Sorry, just entered this field, maybe there are indeed classical approaches for this type of analysis. Thanks!

Entering edit mode
17 months ago
Republic of Ireland

There are "many" options, as expressed by my colleague, Malachi: Drug to Target/Gene/Protein Interaction Databases

His post was > 6 years ago (currently August, 2018), so, a lot of those may have been updated or may not even exist any longer.

Other ones of which I know include:

[Note: open PHACTS links together many other databases.]

My own experience of working with these databases is that they hold much promise.



Login before adding your answer.

Similar Posts
Loading Similar Posts
Powered by the version 2.3.1