Whole exomes - More than 3 time points

Hi,

I am trying to infer clonality in cancers and I am wondering if there are any studies that have done WES for more than three time points for each patient.

Thanks, Kasthuri

next-gen

• 1,025 views • link

written 8.0 years ago by Kasthuri

Chris Miller : is the author of SciClone, described in this publication. I am tagging him.

• 0 views • link

written 8.0 years ago by GenoMax

0 answers

No answers yet.

More posts like this

Clonality Estimates of SCNA in TCGA samples
written 5.5 years ago by christoph.kreitzer93 •

Hi all :) I am willing to use **Somatic Copy Number Alteration** - TCGA data (specifically TCGA-COAD) for some validation studies. I do know that …
Similarity of sequential samples
written 5.9 years ago by skal •

I'm trying to find a way to examine the similarity of sequential samples taken from a patient. Let's say, that I have 10 patients (A, …
How to merge vcf files (output of VarScan2 somatic)?
written 7.6 years ago by Raheleh

Hello, I have WES data of tumor samples with matched ones extracted from 13 patients (paired-end, illumina). I used BWA mem to align them against …
TCGA Copy Number Data in Rdata format
written 8.2 years ago by Kasthuri

Hi, I am working with clonality analysis software in which one of the arguments is seg.mat.loc="tcga.blca.seg.hg19.rdata" It is segmented TCGA copy number data but in …
Loss of Heterozygosity tools for WGS / WES samples
written 8.7 years ago by waqasnayab

Hi, Although, there are many tools available for loss of heterozygosity (LOH) in paired samples (tumor and non-tumor), whether they are WGS or WES. But, …
Time series analysis from ChIP-Seq data
written 8.9 years ago by Assa Yeroslaviz

Hi, I was wondering if there a way to run a time series analysis on ChIP-Seq data. We have duplicates of four different time points …
sciClone + clonEvol on WES
written 9.1 years ago by Kasthuri

I have WES data for 3-time points - germline, diagnosis, and relapse. I can call "somatic" mutations between germline & diagnosis and diagnosis & relapse, …
FFPE trephine DNA for NGS
written 10.4 years ago by CC •

Hi all, this might not be too relevant to bioinformatics, but I am wondering if any of the BioStars members has experience in doing NGS …
Total Size Of Ncrna In Human Genome
written 12.3 years ago by Kasthuri

<p>I am trying to find the total length of ncRNA in the human genome to compare it with the size of coding regions. So far, …
Clustering Gene Expression For Time Course Rna-Seq Data
written 13.7 years ago by Abhi

<p>Hi Guys</p> <p>I am trying to read more about methods available/recommended for clustering gene expression data. Basically the input is a matrix of gene expression …