ddRADseq copy number variation
Hi All,
I was wondering if I can detect copy number variation using ddRAD seq? If so, could recommend some tools to achieve that? And how can I normalize the the data since in a pooled library each sample has 'slightly' different numbers of total reads?
Any comments and suggestions are welcomed!
Thank you!
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I can't "recommend" as I never used, but as it seems you don't know any software, so one is already an improvement:
YMAP: a pipeline for visualization of copy number variation and loss of heterozygosity in eukaryotic pathogens
Caveat: it is designed for small genomes.