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Technology Stack of NCBI (Genbank, GEO, etc.)

Is there a place where I can read about the technology stack used in NCBI, especially in the backend, for their major databases like Genbank, GEO, etc. They are doing an amazing job and I would really like to learn how they do what the do :)

sequence ncbi gene genbank
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updated by Ram Ram • written by navela78 navela78

I don't recall seeing any information about the actual infrastructure (hardware/software) NCBI uses. Information Resources Branch (IRB) appears to be responsible for that aspect. Federal contractors probably do the actual management work.

In a way this is surprising. All of data (with some exceptions) is publicly available but there appears to be a paucity of information about hardware/software NCBI services run on.

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written by GenoMax GenoMax

Yes it is surprising!

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written by navela78 navela78

It would be interesting to know more. This article (2009ish?) has a couple comments from NCBI IEB chief on SRA infrastructure (SQL Server relational meta-db + filesystem storage type design).

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written by Ahill Ahill

Thanks for the article. Do you know anything about genbank?

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written by navela78 navela78

Anyone from NCBI or a contractor for NCBI want to take a shot at this? Perhaps we can start with Genbank ... No need to into details ... just a quick overview of technologies ..

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written by navela78 navela78

I found this article with some information about how NCBI web blast queries are handled technologically.

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written by GenoMax GenoMax

Looks good! They don't explain genbank etc. in such detail.

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written by navela78 navela78

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