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Question: Using R bioconductor for differential gene expression
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I just want to know how to use R bioconductor for the 3 sets of microarray data of schizophrenia and whats it's steps, please answer me?

Thank you.

ADD COMMENTlink 2.1 years ago shuklapriyanka287 • 0 • updated 23 months ago zx8754 7.5k
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If you google the words in the title of your post, you'll find an array of good documentation. Please make some attempt to do some research before asking a question. The result will be better for everyone.

Read the Limma Userguide, as mentioned by Fereshteh, it's like a mini-bible on differential gene expression measurements.

ADD REPLYlink 2.1 years ago
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Hello shuklapriyanka287!

We believe that this post does not fit the main topic of this site.

Too broad.

For this reason we have closed your question. This allows us to keep the site focused on the topics that the community can help with.

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ADD REPLYlink 23 months ago
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First: normalize your data based on the array (CEL or txt)

sharing some naive codes for microarray normalization in R with whom are too new in R alike me

Second: use limma for differential expression

When I did not know how to use R, I used to use geworkbench to do so

Just download and install that, then upload your data and use t-test or so on for differential expression

ADD COMMENTlink 2.1 years ago F ♦ 3.4k
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