CRAM vs BAM
Hello I'd like to know info on BAM and CRAM. Precisely:
What are the main differences between BAM to CRAM?
What are advantages and disadvantages of BAM respects with CRAM and viceversa?
Why BAM is preferred respects to CRAM?
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roccostorace •
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Come on, googling this gives you plenty of output, even links to previous Biostars threads where Heng Li, the leading developer of the original SAM format, comments on this.
It is a case of
tl:ds.Here are the current latest specs:
http://samtools.github.io/hts-specs/CRAMv3.pdf
http://samtools.github.io/hts-specs/SAMv1.pdf
http://www.sanger.ac.uk/science/tools/cram
https://www.ebi.ac.uk/ena/support/cram-tutorial
Partly covered here. Actually CRAM is recommended for long term storage. See here.
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