Variants in excel
I have inherited from a previous study a list of variants in excel. I do no have the original vcf files. What is the best way to analyze the variants in the excel file? I would like to use Varsifter or something similar but most packages seem to require vcf or vs formats. Thank you.
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Based on what I've seen, VCF files tend to be edited majorly by biologists so it might be you can't get them into VCF format again. As genomax says, even a limited VCF file format (i.e. with few INFO and or Genotype fields) might be highly beneficial.
Generally though, Excel is a data grave for all standard text formats.
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Start with moving those out of excel into a standard delimited format file (perhaps they already are). Paste a sample of what you actually have so you can get useful answers.