How to calculate mutation ratio
I am sequencing breast cancer gene and normal gene for breast cancer BRCA 1 and BRCA2. How to calculate the mutation ratio or value between these two genes? Also any open source tool available?
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What have you tried? Can you define mutation ratio for me please?
I have used contiguous pattern mining for healthy and breast cancer data sets. Also I have sequenced exon 11 for chromosome 17. I have calculated the difference between normal pattern n BRCA