Question

From metabolites to genes

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6.3 years ago

ab123 ▴ 50

Hi there,

Are there any recommended tools to determine the genes linked to certain differentially expressed metabolites? Any help much appreciated.

Thank you.

metabolomics genomics • 984 views

ADD COMMENT • link updated 6.3 years ago by Kevin Blighe 87k • written 6.3 years ago by ab123 ▴ 50

score 1 · Answer 1 · 2018-01-17

MetaboAnalyst has an Integrated Pathway Analysis tool that will do this in an indirect fashion. You may want to take a look.

As I understand, we don't yet know the genetic origin of the vast majority of known metabolites, and don't even know the identity of the vast majority of metabolites themselves.

The only other tool that I have come across is commercial and the name slips my mind currently. It was produced by a US-based company and I only heard about it whilst I was working over there.

Kevin