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How to detect insertion and deletion errors from BWA

I am new in using BWA. I will appreciate if someone can let me know how to detect insertion and deletion errors using BWA?

bwa indel errors

bwa is an aligner. For finding differences between your reads and the reference genome you need a variant caller after the alignment, e.g. GATK.

1 answer

Look at some assembly approaches to finding indels. BWA finds short insertions and deletions but using a de novo assembler or similar approach might be better.

You can also check out GATK (https://www.ncbi.nlm.nih.gov/pubmed/21478889/) which has a pipeline for detecting indels. https://www.broadinstitute.org/files/shared/mpg/nextgen2011/nextgen2011_delangel.pdf

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