Entering edit mode
6.4 years ago
jxk906
•
0
Hi, I am trying to clarify whether I can run BaseRecalibration (GATK) step using dbSNPbuild 144 on already calibrated bam files with different dbSNP build (138). I am not sure whether it is advisable or will give a drastic change in variation calling? If I could get an insight on this will be really helpful.
Thanks.