Hello everyone,

I was wondering if someone could help me understand the concept of KEGG modules because I don't seem to be able to fully comprehend it. According to what I read, KEGG modules are manually curated and a repetitive pattern that can be found in different pathways and organisms. Nevertheless, I have a come across a few cases where the genes contained in a module, are not considered genes within the pathway (eg. Pathway hsa00020 and Module hsa_M00003 - gene ENO1 K01689 ).

Why are they not considered? What am I missing?

Thanks in advance