Cufflinks analysis of Tophat BAM file

When I split BAM file by chromosome and then Cufflinks by chromosome-wise takes very less time compared to Cufflinks on whole BAM file. Can somebody help me explain this?

rna-seq alignment

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updated 8.9 years ago by Kevin Blighe

• written 8.9 years ago by qudrat

1 answer

Your RAM and I/O are being used more efficiently when you split the file.

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written 8.9 years ago by Kevin Blighe

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