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how to know the putative function of a gene

I have a list of Differential expressed genes of a particular stress condition was obtained from the microarray. I have to find their putative functions related to that stress condition. how to identify their functions??any web tool to see the putative function of genes??

rna-seq chip-seq genome next-gen gene
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updated by Alex Reynolds Alex Reynolds • written by rajasekargutha • rajasekargutha

I would think tools along the lines of DAVID, GOrrilla or GSEA could put you on your way to finding out general functional categories. They are good tools in well established systems such as cancer biology and hematopoiesis but not as good in areas such as neuroscience, the terms can be somewhat general.

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written by rbronste rbronste

3 answers

If you have gene sequences of the differentially expressed genes, perform blastx against NCBI protein database/Uniprot/closely related species protein sequences, this will help you to get the probable function of the genes.

~ Pooja

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written by poojasethiya poojasethiya

I don't have sequence of genes, only I have the list of gene names.

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written by rajasekargutha • rajasekargutha

Take a look at GeneSCF.

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written by EagleEye EagleEye

If you want ontology and have differentially expressed genes and background genes, look into GOrilla or similar.

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written by Alex Reynolds Alex Reynolds

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