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Shanon Entropy in vcflib

Hi Does anyone know what it means shanon entropy of flanking sequence with respect to vcf files ? https://github.com/vcflib/vcflib#vcfentropy

Does is measures the complexity of the flanking sequence ? means repetitive sequence have high entropy ?

thanks

vcflib entropy vcf
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written by sv91707 sv91707

2 answers

In information theory, Shannon entropy measures the amount of information as the average uncertainty of an event outcome. As applied to sequences, it can be used to measure sequence variability. Therefore, a repetitive sequence has lower entropy than a random sequence.

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written by Jean-Karim Heriche Jean-Karim Heriche

Thanks, I thought so, as I checked a bit. Thanks for the confirmation.

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written by sv91707 sv91707

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