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How to merge 24 ESP vcf files into one?

Hi

I downloaded Exome-seq project's vcf files from below site and would like to merge them into one. (http://evs.gs.washington.edu/EVS/)

I searched tools for merging vcf files but I am facing errors.

In addition, I need to append 'chr' to chromosome since ESP vcfs have no 'chr' prefix.

How to solve this issue?

exome seq project vcf merging
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updated by theobroma22 theobroma22 • written by agicict agicict

I searched tools for merging vcf files but I am facing errors.

What tools did you try? And what errors did you get?

Did you look into VCFtools?

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written by st.ph.n st.ph.n

Hey friend. I'm an international applicant who want to apply for M.S of Computational Biology of CMU. Could you help me to have a glance at one part of my SOP? I'm afraid I don't express things naturally. Thanks!

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written by syndoom1 • syndoom1

1 answer

See this previous post to merge in R: C: Merging of datasets from same tissue/region

To append "chr" to a vector of names called ID in a dataframe stored as a df object in R you can use:

paste0("chr_" , df$ID)
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written by theobroma22 theobroma22

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