How to find proteins annotated with a LIST of GO terms?
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7.1 years ago
keepclam ▴ 10

I have a sequence annotated with several GO terms and I'd like to see if there is a protein eg in UniprotKB or GenBank that is annotated with the same list of terms (not necessarily the same exact list, i.e. the protein from the database can have more GO terms in its annotation). I know that QuickGO can show proteins annotated with a single given term, but as far as I know it doesn't provide the same service with a list.

Is there another tool that can do that?

Gene Ontology annotation • 2.5k views
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7.1 years ago

You can use EnsEMBL BioMart to get genes for a list of GO terms. You'll probably have to post-process the data if you want only genes annotated with all the terms from the list.

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The results I can download are a list of genes annotated with any of the GO terms I feeded it. It looks a lot like the QuickGO approach, but with far more limited datasets available; I could post-process results from looking for a GO slim in QuickGO as well, but that was exactly the thing I wanted to avoid. Or maybe I am missing something?

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