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Smoothing gene expression over a window size

I have a gene, chromosome, position of gene and a mean expression per gene. I would like to calculate ksmoothed mean expression over a window size of 1Mp for every chromosome. Does anybody know how to do this in R?

rna-seq expression
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written by User000 User000

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For anybody interested I found something similar and a good answer in this post: http://stackoverflow.com/questions/37952793/scatter-plot-kernel-smoothing-ksmooth-does-not-smooth-my-data-at-all

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written by User000 User000

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