Structure based phylogenic tree
Hi,
I have to do a structure-based phylogenic tree of proteins for a student project in bioinformatics. Does someone know how to do that ?
Thank you in advance!
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The key is finding a distance function between two genomes. Enjoy your HW.
See this rather old post :
Structure-Based Phylogenetic Analysis
and this artictle below:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135507
Structure-Based Phylogenetic Analysis of the Lipocalin Superfamily
The following paper is 12 years old, but it may be useful as well:
Structure-Based Phylogeny of the Metallo-β-Lactamases
http://aac.asm.org/content/49/7/2778.full