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checking downstream effects of genes

I found a set of highly expressed genes which might be involved in a disease. I did gsea and pathway analysis. I am wondering if any other kind of downstream effects could be analysed in protein level and if there is any good database for that.

rna-seq

This will be highly dependent on what you mean with "might be involved in a disease" and which type of disease you are talking about.

I am talking about cancer.

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