basic experimental methods book for bioinformaticians
I am wondering if the is any basic experimental methods book or review for bioinformaticians so that they can understand the presentations given by experimentalists. Such book should include what kind of experimental methods can be used to validate what kind of in-silico analysis results for example differentially expressed genes, SNPs, pathway enrichment, biomarker targets etc.
0 answers
No answers yet.
Log in to answer this question.
More posts like this
-
Workflow for functional analysis of differential gene core modules: KEGG, GSEA, and GO enrichment
written by mizzika •
-
Diference between Co-expressed gene-set enrichment analysis (COGENA) and gene-set enrichment analys…
written by omargmc.tak •
-
Single cell
written by synat.keam •
-
Methods to interrogate RNA-seq
written by telroyjatter
-
Functional analysis of RNASeq differentially expressed genes
written by Colari19
-
DE and enrichment analysis pipeline
written by Pappu
-
Downstream applications of Differential transcript expression
written by firestar
-
Permanent/Long Term Jobs In Bioinformatics
written by Pappu
-
Pointers To Learn About Functional Enrichment And Go Analysis
written by aravind ramesh
-
What Are The Most Reliable Normalization Methods For Microarrays?
written by Jarretinha
What are sentimentalists?
Experimentalists with an irrationally emotional attachment to their hypotheses...
Well then, by your definition, whatever you do won't help to change their minds. Besides, this terminology is not helpful, on the contrary, is alienating. You are just making your task harder if you start by calling derogatory names the people you want to convince.Sorry, didn't see the question and comment are from different people, so I didn't get the joke.
A simple book could be hard to create, each methodology is based on a lot of biological knowledge. Even biologists don't understand the methods they do, many experiments are based on "faith". Coming from a wet lab I know many people cannot explain the methods, like "don't do a PCR on a moon night because it will not work" or "sing a lullaby to the plant embryos to have a better transformation rate".
I don’t think there is likely to be a satisfactory answer to this question, but the Gospel of molecular biology which you’ll find all 3 volumes of in any self-respecting mol bio lab is Sambrook et al: https://hum-molgen.org/literature/12-2000/000001.html
If there’s a molecular technique (qPCR, cloning, protein work etc.) its in that book (or I should say books).