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Ancestral alleles in sheep

Hi,

I was hoping to examine several sheep populations for selection signatures and was hoping to use the iHS method. From what I can see the ancestral and derived alleles are required but these are unknown in sheep? How do you proceed with this type of analyses if the ancestral alleles are unknown?

Many thanks

ihs selection signatures ancestral alleles

Have you tried counting sheep?

(sorry i couldn't help myself)

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