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https://en.wikipedia.org/wiki/Tandem_mass_spectrometry
http://www.proteomics.com/docs/Proteome_Brochure_MS3Workflow_LTR-7.pdf
@genomax2 thank, the description is a bit bizarre, lets assume TMT , you should label it and it is measured in LC-MS-MS, means it is MS2 but it is many times written label free!!! is it right ?