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ASCAT for zebrafish samples

Hi! I want to explore the idea of running ASCAT on zebrafish tumor/normal samples. I know that it is hard wired for use with the human genome. How can I make it compatible to use with the zebrafish genome?

Additionally, I wish to infer whole genome duplication events in our tumor samples. Is ASCAT a good tool for that? How is ASCAT different from the Broad institute's ABSOLUTE program?

genome duplication copy number tumor ploidy

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