For protein binding microarrays, how do you extract an 8mer sequence from your 35mer sequence?
I'm having trouble finding papers that describe how to convert a 35mer sequence to the 8mer motif representative of a TF binding sequence (given a dataset of 35mer motifs and the mean signal intensity). If anyone has additional resources for this, would you be able to refer me to it?
Thanks!
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I found two papers for you to look at:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020059
https://arxiv.org/ftp/arxiv/papers/1312/1312.4576.pdf
Hopefully they will help you.