This is a test version of Biostars. For the public version, visit https://www.biostars.org.
feature selection for specific disease groups

Hi all,

I am looking for a method/tool - I have 7 different disease groups and normal. What I want to do is find genes that are specific to particular disease groups.

Anyone familiar with a method?

Thanks in advance!

Mamta

feature-selection gene-expression
• 2,508 views • link
updated by Ram Ram • written by datanerd datanerd

What data do you have on each group?

• 0 views • link
written by Ram Ram

You'll need to define what you mean by "specific".

• 0 views • link
updated by Ram Ram • written by Sean Davis Sean Davis

Hi guys,

Sorry wasn't too clear before. So what I need to find is that "groups of genes" whose expression is changing in terms of normal in one group and is specific to that particular group. And other disease groups don't share that same group of genes changing.

Any papers that might have done something similar??

Thanks in advance!!

Mamta

• 0 views • link
updated by Ram Ram • written by datanerd datanerd

1 answer

Without knowing why you want these sets of genes, have a look at using limma and decideTests().

• 0 views • link
updated by Ram Ram • written by Sean Davis Sean Davis

Log in to answer this question.

More posts like this