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Tools to compute Lorenz curve of coverage uniformity

I would like to compute a Lorenz curve of per-base coverage depth for a BAM file on a certain BED file. I can find a way to do it by myself, but it would be great if you could point me to some existing software.

Thank you in advance!

bam genome alignment

3 answers

Hi Igor,

I wrote a python tool to do so:

https://github.com/yhoogstrate/bam-lorenz-coverage

all best,

Youri

htSeqTools (with giniCoverage function) seems the only ready-to-use tool I have found for this task. However, it does not allow to restrict the analysis on a specific region (for example, by using a BED file).

https://blog.addgene.org/ngs-quality-control-for-pooled-libraries you can check the comments there is a comment by will including a link which is plsa.py

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