Shrinking fold change and dispersion for RNA-seq data ( DESeq2)
Hello biostars,
I'm new to RNA-seq and I'm trying to introduce myself to DESeq2.
My question is: Why do we need to shrink the fold change and dispersion for RNA-seq data?
Thanks in advance
• 5,185 views
•
link
updated
by
Ram
•
written
by
schmilblik •
•
written
by
schmilblik •
1 answer
I'd recommend trying to read the DESeq2 paper from 2014 (we wrote it with non-statisticians in mind), but you might also try this post on another thread:
A: Can someone please explain in simple terms how DESeq2 works?
• 0 views
•
link
written
by
Michael Love
Log in to answer this question.
More posts like this
-
log2 fold change in RNA-seq analysis
written by wmsalsah •
-
DESeq2 input file
written by Bioinf_Questions •
-
cuffdiff output table
written by Balatheskulter •
-
RNA-seq Differential Gene Analysis
written by mlai2567 •
-
RNA-seq DE genes visualization in genome browser
written by pierre.pericard •
-
RNA-Seq, why estimate the distribution of your data?
written by tmms •
-
Data integration - STRINGdb graph -
written by schmilblik •
-
pipeline of analyses to identify functional loops of chromosomes
written by schmilblik •
-
Single-cell RNA-seq : for what questions ? and what are the classical pipelines ?
written by schmilblik •
-
Differential expression with CQN normalized RNA-seq data
written by swkim •
