This is a test version of Biostars. For the public version, visit https://www.biostars.org.
Building An Average Consensus Structure

I have a 4 pdbs which have at least 85% sequence similarity from the query sequence. What would be the easiest way to build an average structure from the four pdbs?

pdb consensus
• 2,020 views • link
updated by João Rodrigues João Rodrigues • written by Harpalss Harpalss

1 answer

I don't know how valuable that information might be. If you try to average atomic coordinates you'll end up having, most likely, clashes and bumps, not to mention overall artificial stereochemistry. You're probably better off building a homology model based on 4 templates using MODELLER for example. There is an example in their tutorial where they use 4 templates to build a model - Advanced Modelling.

• 0 views • link
written by João Rodrigues João Rodrigues

Log in to answer this question.

More posts like this