I am making some research on protein interaction network for Colorectal Cancer. Next step after creation of this network was GO and Pathway functional annotation of the genes.
For this purpose I've been using the these tools: KOBAS, DAVID, Enrichr, GOrilla. I've read a few explanations how tools is working, but I still don't know how to understand and use the OUTPUT data generated by these tools. Most of this tools give same output. My aim is to find the most significant terms, to identify genes that are involved in these terms and after that based on the results to set up some hypotheses about which of the genes can be used as a biomarkers for Colorectal Cancer.
I know that this is not easy, but anybody to help me with some links, tutorials, explanations?
In addition I am sending the link for GOrilla and KOBAS output:
GOrilla: http://cbl-gorilla.cs.technion.ac.il/GOrilla/gai68pln/GOResults.html
KOBAS: http://kobas.cbi.pku.edu.cn/guest.job.do?outputID=395776
