Uses of HMMER in bioinformatics
I am a CSE student and I am entitled a project on running Hmmer on MIC Architecture. For this, I have started reading HMMER and what it does. What I am unable to comprehend is, why and where is protein sequence alignment and identifying protein homologous necessary?
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When you get homologous regions from allignment across the families or species, then they are Conserved domains.Conserved domains in proteins play a crucial role in protein interactions, DNA binding, enzyme activity, and other important cellular processes.
I mean they are very very important for survival.
Please read some review article regarding this.
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